Federated learning (FL) enables distributed model training across edge devices while preserving data locality. This decentralized approach has emerged as a promising solution for collaborative learning on sensitive user data, effectively addressing the longstanding privacy concerns inherent in centralized systems. However, the decentralized nature of FL exposes new security vulnerabilities, especially backdoor attacks that threaten model integrity. To investigate this critical concern, this paper presents the Layer Smoothing Attack (LSA), a novel backdoor attack that exploits layer-specific vulnerabilities in neural networks. First, a Layer Substitution Analysis methodology systematically identifies backdoor-critical (BC) layers that contribute most significantly to backdoor success. Subsequently, LSA strategically manipulates these BC layers to inject persistent backdoors while remaining undetected by state-of-the-art defense mechanisms. Extensive experiments across diverse model architectures and datasets demonstrate that LSA achieves a remarkably backdoor success rate of up to 97% while maintaining high model accuracy on the primary task, consistently bypassing modern FL defenses. These findings uncover fundamental vulnerabilities in current FL security frameworks, demonstrating that future defenses must incorporate layer-aware detection and mitigation strategies.

Artificial intelligence (AI) has shown great potential in medical imaging, particularly for brain tumor detection using Magnetic Resonance Imaging (MRI). However, the models remain vulnerable at inference time when they are trained collaboratively through Federated Learning (FL), an approach adopted to protect patient privacy. Adversarial attacks can subtly alter medical scans in ways invisible to the human eye yet powerful enough to mislead AI models, potentially causing serious misdiagnoses. Existing defenses often assume centralized data and struggle to cope with the decentralized and diverse nature of federated medical settings. In this work, we present MedFedPure, a personalized federated learning defense framework designed to protect diagnostic AI models at inference time without compromising privacy or accuracy. MedFedPure combines three key elements: (1) a personalized FL model that adapts to the unique data distribution of each institution; (2) a Masked Autoencoder (MAE) that detects suspicious inputs by exposing hidden perturbations; and (3) an adaptive diffusion-based purification module that selectively cleans only the flagged scans before classification. Together, these steps offer robust protection while preserving the integrity of normal, benign images. We evaluated MedFedPure on the Br35H brain MRI dataset. The results show a significant gain in adversarial robustness, improving performance from 49.50% to 87.33% under strong attacks, while maintaining a high clean accuracy of 97.67%. By operating locally and in real time during diagnosis, our framework provides a practical path to deploying secure, trustworthy, and privacy-preserving AI tools in clinical workflows. Index Terms: cancer, tumor detection, federated learning, masked autoencoder, diffusion, privacy

Vision-language models like CLIP demonstrate impressive zero-shot generalization but remain highly vulnerable to adversarial attacks. In this work, we propose Confidence-Aware Weighting (CAW) to enhance zero-shot robustness in vision-language models. CAW consists of two components: (1) a Confidence-Aware loss that prioritizes uncertain adversarial examples by scaling the KL divergence between clean and adversarial predictions, and (2) a feature alignment regularization that preserves semantic consistency by minimizing the distance between frozen and fine-tuned image encoder features on adversarial inputs. These components work jointly to improve both clean and robust accuracy without sacrificing generalization. Extensive experiments on TinyImageNet and 14 additional datasets show that CAW outperforms recent methods such as PMG-AFT and TGA-ZSR under strong attacks like AutoAttack, while using less memory.

Randomized smoothing is a well-established method for achieving certified robustness against l2-adversarial perturbations. By incorporating a denoiser before the base classifier, pretrained classifiers can be seamlessly integrated into randomized smoothing without significant performance degradation. Among existing methods, Diffusion Denoised Smoothing - where a pretrained denoising diffusion model serves as the denoiser - has produced state-of-the-art results. However, we show that employing a denoising diffusion model introduces a covariate shift via misestimation of the added noise, ultimately degrading the smoothed classifier's performance. To address this issue, we propose a novel adversarial objective function focused on the added noise of the denoising diffusion model. This approach is inspired by our understanding of the origin of the covariate shift. Our goal is to train the base classifier to ensure it is robust against the covariate shift introduced by the denoiser. Our method significantly improves certified accuracy across three standard classification benchmarks - MNIST, CIFAR-10, and ImageNet - achieving new state-of-the-art performance in l2-adversarial perturbations. Our implementation is publicly available at https://github.com/ahedayat/Robustifying-DDS-Against-Covariate-Shift