LLM-based agents execute real-world workflows via tools and memory. These affordances enable ill-intended adversaries to also use these agents to carry out complex misuse scenarios. Existing agent misuse benchmarks largely test single-prompt instructions, leaving a gap in measuring how agents end up helping with harmful or illegal tasks over multiple turns. We introduce STING (Sequential Testing of Illicit N-step Goal execution), an automated red-teaming framework that constructs a step-by-step illicit plan grounded in a benign persona and iteratively probes a target agent with adaptive follow-ups, using judge agents to track phase completion. We further introduce an analysis framework that models multi-turn red-teaming as a time-to-first-jailbreak random variable, enabling analysis tools like discovery curves, hazard-ratio attribution by attack language, and a new metric: Restricted Mean Jailbreak Discovery. Across AgentHarm scenarios, STING yields substantially higher illicit-task completion than single-turn prompting and chat-oriented multi-turn baselines adapted to tool-using agents. In multilingual evaluations across six non-English settings, we find that attack success and illicit-task completion do not consistently increase in lower-resource languages, diverging from common chatbot findings. Overall, STING provides a practical way to evaluate and stress-test agent misuse in realistic deployment settings, where interactions are inherently multi-turn and often multilingual.

The release of open-weight large language models (LLMs) creates a tension between advancing accessible research and preventing misuse, such as malicious fine-tuning to elicit harmful content. Current safety measures struggle to preserve the general capabilities of the LLM while resisting a determined adversary with full access to the model's weights and architecture, who can use full-parameter fine-tuning to erase existing safeguards. To address this, we introduce AntiDote, a bi-level optimization procedure for training LLMs to be resistant to such tampering. AntiDote involves an auxiliary adversary hypernetwork that learns to generate malicious Low-Rank Adaptation (LoRA) weights conditioned on the defender model's internal activations. The defender LLM is then trained with an objective to nullify the effect of these adversarial weight additions, forcing it to maintain its safety alignment. We validate this approach against a diverse suite of 52 red-teaming attacks, including jailbreak prompting, latent space manipulation, and direct weight-space attacks. AntiDote is upto 27.4\% more robust against adversarial attacks compared to both tamper-resistance and unlearning baselines. Crucially, this robustness is achieved with a minimal trade-off in utility, incurring a performance degradation of upto less than 0.5\% across capability benchmarks including MMLU, HellaSwag, and GSM8K. Our work offers a practical and compute efficient methodology for building open-weight models where safety is a more integral and resilient property.